When you slide your finger over an object, the friction and vibration that occur depending on the surface condition of the object will cause sensations such as roughness or smoothness. Therefore, in order to achieve human-centered manufacturing through the reproduction of realistic tactile sensations, it is necessary to clarify in detail the effects of the surface conditions of objects on the sliding friction characteristics of fingers and human tactile sensations. In this study, we focus on surface roughness shapes such as unevenness and chemical properties such as organic molecule modification, with the aim of clarifying the effects of changes in the surface conditions of objects on the sliding friction behavior of fingers and human tactile sensations.